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. 2019 Jan 11;5:138. doi: 10.3389/fnut.2018.00138

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Copyright © 2019 Tuyaerts, Rombauts, Everaert, Van Nuffel and Amant.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of curcumin supplementation on COX-2 expression. COX-2 expression in PBMC was determined by flow cytometry. The graphs show the expression in the monocyte (CD14⁺) gate, either expressed as percentage of cells expressing COX-2 (A,C) or as MFI of COX-2 expression levels (B,D). (A,B) Show the expression of COX-2 in PBMC directly after thawing, while (C,D) show COX-expression levels after a 5h-in vitro culture period in the presence of LPS. Each line depicts one patient. Time points are as follows: T0-baseline, T1-day 1 of treatment, T2-day 7 of treatment, T3-day 14 of treatment, T4, 1 week after last CP dose.