Table 5.
Pathways significantly enriched in fetal and newborn cardiac following ssGSEA
Number of Significant Genes (FDR-corrected P < 0.10) |
|||||
---|---|---|---|---|---|
Pathway | P value | FDR-corrected P value | Relative Abundance | F > N | N > F |
Purine metabolism | 2.42E−05 | 4.35E−04 | N > F | 5 | 17 |
Oxidative phosphorylation | 2.10E−04 | 1.26E−03 | N > F | 23 | 31 |
Fatty acid metabolism | 6.64E−04 | 2.39E−03 | N > F | 18 | 21 |
Peroxisome | 8.40E−04 | 2.52E−03 | N > F | 8 | 10 |
Glycerophospholipid metabolism | 5.74E−03 | 0.01 | N > F | 3 | 8 |
Nitrogen metabolism | 1.22E−04 | 1.10E−03 | F > N | 2 | 1 |
Butanoate metabolism | 3.50E−04 | 1.58E−03 | F > N | 9 | 2 |
Glycolysis | 5.82E−03 | 0.01 | F > N | 6 | 10 |
Propanoate metabolism | 5.99E−03 | 0.01 | F > N | 8 | 2 |
FDR, false discovery rate; ssGEA, single-sample gene enrichment analysis.