Fig. 2.
Effect of dehydroepiandrosterone (DHEA) on the current-voltage (I-V) relationship of L-type Ca2+ current (ICa,L). A: holding potential (HP) of −80 mV. a–d refer to typical current traces, e is the I-V of peak current density (ICa,L,peak) (n = 23), and f is the I-V of current density at 500 ms (ICa,L,500) (n = 18). B: HP of −40 mV. a–d show typical traces, and e is the I-V of ICa,L,peak when n = 9. I-V relationships were fitted with the Botzmann equation as per the parameters shown in Table 1. WO, washout.