Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 25;315(6):H1614–H1626. doi: 10.1152/ajpheart.00277.2018

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 the American Physiological Society

PMC Copyright notice

Fig. 6. — Aortic valves from cadherin 11 (Cdh11) transgenic mice have reduced calcification and similar trends in myofibroblast and inflammatory markers as observed in vitro. A−G: histology (A and B) and immunofluorescence (C–G) of Cdh11^+/+, Cdh11^+/−, and Cdh11^−/− murine aortic valves. Calcification was reduced with loss of CDH11 (A and B). CDH11 expression was inversely correlated with smooth muscle α-actin (α-SMA; C) and CDH2 (D) but positively correlated with IL-6 (E) and the fraction of phosphorylated STAT3 (F and G). Arrows denote leaflets. Blue indicates DAPI-stained nuclei. Scale bars = 500 µm.