Table 2.
Differentially expressed genes in chronic myocardial ischemia versus control groups
| Gene Name | Mean FPKM Control | Mean FPKM Chronic MI | Log2(Fold Change) | Adjusted P Value |
|---|---|---|---|---|
| ENSSSCG00000036836 | 193.397 | 729.194 | 1.91474 | 0.027325 |
| EGR3 | 7.29248 | 20.6288 | 1.50018 | 0.027325 |
| CXCL2 | 8.08219 | 22.2903 | 1.4636 | 0.027325 |
| COL6A5 | 0.758159 | 2.07294 | 1.45111 | 0.027325 |
| NR4A3 | 1.96634 | 4.98727 | 1.34274 | 0.027325 |
| CENPE | 0.620469 | 1.51267 | 1.28567 | 0.027325 |
| SFRP4 | 6.32537 | 14.7165 | 1.21822 | 0.027325 |
| MPZ | 9.85831 | 22.9047 | 1.21623 | 0.027325 |
| NR4A1 | 27.2766 | 58.999 | 1.11302 | 0.027325 |
| NR4A2 | 5.45997 | 11.4228 | 1.06495 | 0.027325 |
| MGP | 15.6685 | 32.3172 | 1.04443 | 0.027325 |
| PMP2 | 303.429 | 605.926 | 0.997784 | 0.027325 |
| ENSSSCG00000007527 | 4.52509 | 8.88267 | 0.973046 | 0.027325 |
| CHRNA4 | 3.15805 | 6.07507 | 0.943868 | 0.027325 |
| FosB | 24.2775 | 45.4682 | 0.90524 | 0.027325 |
| BTG2 | 18.6393 | 34.1701 | 0.874389 | 0.027325 |
| TLCD2 | 25.5482 | 46.8275 | 0.874137 | 0.027325 |
| ADAMTS1 | 6.78085 | 11.8755 | 0.808449 | 0.027325 |
| COX7B | 49.1576 | 85.0035 | 0.790108 | 0.027325 |
| MX2 | 14.1256 | 8.11949 | −0.798851 | 0.027325 |
| OAS2 | 24.9147 | 13.8876 | −0.843199 | 0.027325 |
| FAM84A | 27.784 | 14.4033 | −0.947857 | 0.027325 |
| SAMD9 | 4.79184 | 2.44723 | −0.969431 | 0.027325 |
| RGS20 | 1.99631 | 1.00276 | −0.993358 | 0.027325 |
| PANX1 | 4.00116 | 1.95053 | −1.03655 | 0.027325 |
| ISG15 | 22.6618 | 10.2576 | −1.14357 | 0.027325 |
| ACTC1 | 8.42141 | 3.80225 | −1.14721 | 0.027325 |
| HTR2A | 2.14839 | 0.917864 | −1.2269 | 0.027325 |
| TEAD4 | 6.03033 | 2.37845 | −1.34221 | 0.027325 |
| GLDN | 5.86291 | 1.69466 | −1.79063 | 0.027325 |
| RSAD2 | 5.45731 | 1.42844 | −1.93375 | 0.027325 |
| TNFSF18 | 9.39156 | 1.7066 | −2.46024 | 0.027325 |
| TNFAIP3 | 2.88778 | 5.36972 | 0.894886 | 0.0465106 |
| PARP12 | 4.87329 | 2.85286 | −0.772488 | 0.0465106 |
| KLF4 | 5.44863 | 9.78261 | 0.844327 | 0.0636699 |
| ENSSSCG00000033089 | 2.82248 | 1.57891 | −0.838032 | 0.0636699 |
| CMPK2 | 4.91795 | 2.56769 | −0.937588 | 0.0636699 |
| RASL11B | 2.89599 | 1.39235 | −1.05654 | 0.0636699 |
| IGFBP6 | 25.4766 | 45.5083 | 0.836957 | 0.0787748 |
| PDK4 | 37.893 | 57.5803 | 0.603646 | 0.0787748 |
| MX1 | 46.1784 | 29.198 | −0.66135 | 0.0787748 |
| ENSSSCG00000022246 | 4.19374 | 7.09691 | 0.758953 | 0.086746 |
| ARID5A | 12.0509 | 7.00777 | −0.782113 | 0.086746 |
| ZBP1 | 4.03983 | 1.55017 | −1.38186 | 0.086746 |
| C1QTNF7 | 2.39948 | 0.914228 | −1.3921 | 0.086746 |
| CSF3 | 0.493867 | 2.20436 | 2.15816 | 0.0993636 |
Differentially expressed genes between chronic myocardial ischemia (MI; n = 8) and control pigs (n = 10) with adjusted P values of <0.1 are shown. Adjusted P value, adjusted P value by Benjamini-Hochberg; FPKM, fragments per kilobase per million mapped reads.