Periostin increased the expression of αV-integrins and β3-integrins in autosomal dominant polycystic kidney disease (ADPKD) cells. ADPKD cells were grown on Transwells and incubated in Cont or Postn for 6 or 24 h. A: representative immunoblots show protein levels of αV-, β3-, and β1- integrins and GAPDH. Graphs (means ± SE) display the relative expression of αV-integrin/GAPDH (B), β3-integrin/GAPDH (C), and β1-integrin/GAPDH (D). *P < 0.05, **P < 0.01, compared with Cont (set to 1.0).