Table 3.
Summary of calculated incidence rates for bleeding related to colonoscopy from recent studies with sample sizes > 50,000 cases n (%)
| Ref. | Duration of enrollment | Study design (data source) | Publication year | Country | Colonoscopies performed | Bleeding |
| Sieg et al[27] | 1998-1999 | Prospective study | 2001 | Germany | 82416 | 1 (0.001) |
| Rabeneck et al[77] | 2002-2003 | Population-based cohort study | 2008 | Canada | 97091 | 137 (0.141) |
| Bokemeyer et al[45] | 2003-2006 | Study based on German online registry | 2009 | Germany | 269144 | 442 (0.164) |
| Crispin et al[46] | 2006 | Study based on compulsory health insurance (CHI) | 2009 | Germany | 236087 | 520 (0.220) |
| Warren et al[47] | 2001-2005 | Population-based, matched cohort study | 2009 | United States | 53220 | 340 (0.639) |
| Rabeneck et al[78] | 2002-2003 | Population-based cohort study | 2011 | Canada | 67632 | 83 (0.123) |
| Pox et al[30] | 2003-2008 | Prospective cross-sectional study | 2012 | Germany | 2821392 | 573 (0.020) |
| Blotière et al[29] | 2010 | Study based on comprehensive French health insurance data (SNIIRAM) | 2014 | France | 947061 | 933 (0.099) |
| Rutter et al[52] | 2006-2012 | Study based on English National Health Service Bowel Cancer Screening Program (NHSBCSP) | 2014 | United Kingdom | 130831 | 291 (0.222) |
| Zafar et al[48] | 2007-2008 | Health Insurance Portability and Accountability Act compliant study | 2014 | United States | 54039 | 371 (0.687) |