FIGURE 2.

Temporal resolution during early migratory events. MPIOs (50 μL) were injected into the anterior horn of the lateral ventricle proximal to the SVZ in healthy adult rats. 3D gradient echo images of a rat brain were serially acquired at 1 h, 1 days, 3 days, 6 days, and 12 days (A) post injection. The RMS is visible on the day 1 images as a dark line extending from the ventricle (white arrow). Migration across the entire OB is visible by day 12, the 3D volume rendering of the OB (B) shows the extent of cells within the structure (Adapted from Shuboni-Mulligan et al., 2018).