FIGURE 5.

Histology demonstrating the cell types of NPCs after differentiation in vivo. NPCs are double-labeled with BrdU (red) and either β-tubulin (green, A) showing that cells are differentiation into neurons. Cells that have differentiated into astrocytes are double-labeled with BrdU (red) and GFAP (Green, B). While those cells that have differentiated into oligodendrocytes are triple-labeled for hNSC (red), CNPase (green), and the nucleus with DAPI (blue C). However, there is very little macrophages-positive staining (OX6, Green) that is co-localized for BrdU (red, D). [Data from Guzman et al., 2008, reproduced with permission); Daadi et al., 2008, Reproduced via Plos One Creative Commons Attribution (CC BY) license].