Table 4.
Combined effect of clinically used antibiotics with 1–5 against multidrug-resistant strains. Minimal inhibitory concentration (MICs) are expressed in mg/L.
| E. coli SA/2 (ESBL) | E. faecalis B3/101 (VRE) | S. aureus 66/1 (MRSA) | ||||
|---|---|---|---|---|---|---|
| CTX | VAN | OXA | ||||
| Compound | Distribution | MIC | Distribution | MIC | Distribution | MIC |
| Antibiotic | - | 512 | - | 1024 | - | 64 |
| Antibiotic +1 | - | 512 | - | 1024 | - | 64 |
| Antibiotic +2 | - | 128 | - | 1024 | - | 128 |
| Antibiotic +3 | - | 512 | - | 1024 | - | 64 |
| Antibiotic +4 | - | 512 | - | 1024 | - | 64 |
| Antibiotic +5 | - | 512 | - | 1024 | - | 64 |
MIC, minimal inhibitory concentration; (-), no inhibition halo or no increase in the inhibition halo; CTX, cefotaxime; VAN, vancomycin; OXA, oxacillin; ESBL, extended-spectrum β-lactamase producer; VRE, vancomycin-resistant Enterococcus; MRSA, methicillin-resistant Staphylococcus aureus.