| AGS | Aicardi-Goutières Syndrome |
| AhR | aryl hydrocarbon receptor |
| APC | antigen presenting cells |
| BBB | blood brain barrier |
| BM | bone marrow |
| CNS | central nervous system |
| CSF | cerebrospinal fluid |
| CSF-1 | colony-stimulating factor-1 |
| DAMP | damage-associated molecular pattern |
| DC | dendritic cell |
| DDX | DEAD-box helicase |
| EAE | experimental autoimmune encephalomyelitis |
| GFP | green fluorescence protein |
| HSVTK | herpes simplex virus thymidine kinase |
| iDTR | inducible diphtheria toxin receptor |
| IFN | interferon |
| IFNAR | interferon α receptor |
| iNOS | inducible nitric oxide synthase |
| IRF | interferon regulatory factor |
| ISG | interferon-stimulated gene |
| JAK | Janus kinase |
| LPS | lipopolysaccharide |
| MIF | macrophage migration inhibitory factor |
| MDM | Monocyte-derived macrophages |
| MiDM | Microglia-derived macrophages |
| MOG | myelin oligodendrocyte glycoprotein |
| MRI | magnetic resonance imaging |
| MS | multiple sclerosis |
| NK cell | natural killer cell |
| NMO | neuromyelitis optica |
| OPC | oligodendrocyte progenitor cells |
| OSC | organotypic slice cultures |
| PAMP | pathogen-associated molecular pattern |
| PET | positron emission tomography |
| poly(I:C) | polyinosinic:polycytidylic acid |
| PPMS | primary-progressive multiple sclerosis |
| PRR | pattern recognition receptor |
| RFP | red fluorescence protein |
| RLH | Retinoic acid inducible gene (RIG)-I like helicase |
| RRMS | relapsing-remitting multiple sclerosis |
| Runx1 | Runt-related transcription factor 1 |
| SOCS | suppressor of cytokine signaling |
| STAT | signal transducer and activator of transcription |
| TGFα | transforming growth factor α |
| Th cell | T helper cell |
| TLR | toll-like receptor |
| TNF | tumor necrosis factor |
| TREM2 | triggering receptor also expressed on myeloid cells-2 |
| TRIF | TIR domain containing adapter inducing interferon beta |
| TSPO | translocator protein |
| USP | ubiquitin specific protease |
| VEGF | vascular endothelial growth factor |
| VLA-4 | very late antigen-4 |
| WT | wildtype |
| YFP | yellow fluorescence protein |
| YS | yolk sac |