AGS |
Aicardi-Goutières Syndrome |
AhR |
aryl hydrocarbon receptor |
APC |
antigen presenting cells |
BBB |
blood brain barrier |
BM |
bone marrow |
CNS |
central nervous system |
CSF |
cerebrospinal fluid |
CSF-1 |
colony-stimulating factor-1 |
DAMP |
damage-associated molecular pattern |
DC |
dendritic cell |
DDX |
DEAD-box helicase |
EAE |
experimental autoimmune encephalomyelitis |
GFP |
green fluorescence protein |
HSVTK |
herpes simplex virus thymidine kinase |
iDTR |
inducible diphtheria toxin receptor |
IFN |
interferon |
IFNAR |
interferon α receptor |
iNOS |
inducible nitric oxide synthase |
IRF |
interferon regulatory factor |
ISG |
interferon-stimulated gene |
JAK |
Janus kinase |
LPS |
lipopolysaccharide |
MIF |
macrophage migration inhibitory factor |
MDM |
Monocyte-derived macrophages |
MiDM |
Microglia-derived macrophages |
MOG |
myelin oligodendrocyte glycoprotein |
MRI |
magnetic resonance imaging |
MS |
multiple sclerosis |
NK cell |
natural killer cell |
NMO |
neuromyelitis optica |
OPC |
oligodendrocyte progenitor cells |
OSC |
organotypic slice cultures |
PAMP |
pathogen-associated molecular pattern |
PET |
positron emission tomography |
poly(I:C) |
polyinosinic:polycytidylic acid |
PPMS |
primary-progressive multiple sclerosis |
PRR |
pattern recognition receptor |
RFP |
red fluorescence protein |
RLH |
Retinoic acid inducible gene (RIG)-I like helicase |
RRMS |
relapsing-remitting multiple sclerosis |
Runx1 |
Runt-related transcription factor 1 |
SOCS |
suppressor of cytokine signaling |
STAT |
signal transducer and activator of transcription |
TGFα |
transforming growth factor α |
Th cell |
T helper cell |
TLR |
toll-like receptor |
TNF |
tumor necrosis factor |
TREM2 |
triggering receptor also expressed on myeloid cells-2 |
TRIF |
TIR domain containing adapter inducing interferon beta |
TSPO |
translocator protein |
USP |
ubiquitin specific protease |
VEGF |
vascular endothelial growth factor |
VLA-4 |
very late antigen-4 |
WT |
wildtype |
YFP |
yellow fluorescence protein |
YS |
yolk sac |