Transcription regulation |
5S rRNA acting on transcription factor for polymerase factor IIIA |
Inhibits activation of RNA polymerase III-dependent transcription and related genes |
Translation regulation |
Ribosomal protein fragments |
siRNA and RNAi inhibiting mRNA translation |
Permits read-through of termination codons |
23S rRNA fragment |
Inhibits release factor 2 (RF2)-dependent translation termination |
Protein activity control |
5S rRNA-RPL5-RPL11 complex |
Inhibits the Hdm2 protein which in turn regulates p53 |
Sources of novel transcripts |
5.8S and 28S rRNA fragments |
Translated into proteins |