Table 6.

The pharmacokinetic parameters of CPS, RNG, and RNC in rats after oral administration of complanatuside ($\overline{X}\pm S$, n = 8).

Analytes	Cmax (ng/mL)	Tmax (h)	t1/2 (h)	AUC(0-t) (µg/L·h)	AUC(0-∞) (µg/L·h)	MRT(0-t) (h)
CPS	119.15 ± 11.25	1.00 ± 0.36	0.51 ± 0.04	143.52 ± 15.73	143.52 ± 15.73	1.72 ± 0.19
RNG	111.64 ± 14.68	3.00 ± 0.25	1.33 ± 0.55	381.73 ± 24.13	387.21 ± 28.06	4.28 ± 0.55
RNC	1122.18 ± 113.32	5.33 ± 0.63	4.15 ± 0.49	6540.14 ± 433.70	6627.61 ± 471.83	4.99 ± 0.11

CPS: complanatuside; RNG: rhamnocitrin 3-O-β-glc; RNC: rhamnocitrin; C_max: the maximum plasma concentration; T_max: the time to reach the maximum drug concentration; t_1/2: half-life; AUC: the area under the plasma concentration-time curve; MRT: the mean residence time.