Table A5.

Correlation coefficient (r²) and mean differences (MD) of n-octanol/water partition coefficient (log P_ow,calc) to log P_ow,exp measured at different pH and calculated lipid/water partition coefficient (log P_lw,calc) in model membranes.

Parameter	pH	log Pow,calc				log Plw,calc
		COSMOtherm	Molinspiration	AlogP		CER	DOPC	CLC
r2	4.5	0.68	0.83	0.74		0.82	0.84	0.79
	5.5	0.68	0.83	0.74		0.82	0.84	0.79
	6.5	0.67	0.87	0.74		0.79	0.81	0.75
	7.5	0.66	0.87	0.77		0.81	0.82	0.76
	8.5	0.61	0.71	0.87		0.78	0.77	0.75
MD	4.5	0.83	0.78	0.21		0.26	0.49	0.69
	5.5	0.84	0.78	0.21		0.26	0.50	0.69
	6.5	0.90	0.66	0.19		0.24	0.58	0.62
	7.5	1.02	0.47	0.27		0.32	0.75	0.51
	8.5	1.08	0.35	0.32		0.37	0.90	0.44