Table 2.
Protein expression in endometriosis and controls.
| Protein | Absolute Value | Absolute Value | Absolute Value | p-Value | p-Value |
|---|---|---|---|---|---|
| Endometriosis | MC | HC | Endometriosis vs. MC | Endometriosis vs. HC | |
| N = 94 | N = 47 | N = 28 | |||
| AXIN1 | 4.1 ± 1.2 | 2.7 ± 1.3 | 2.7 ± 1.0 | <0.001 | 0.001 |
| ST1A1 | 2.8 ± 1.1 | 1.8 ± 1.2 | 1.5 ± 0.8 | 0.001 | 0.010 |
| CXCL9 | 7.1 ± 0.7 | 8.7 ± 0.9 | 8.4 ± 0.7 | <0.001 | <0.001 |
| CD40 | 9.4 ± 0.6 | 9.2 ± 0.4 | 9.1 ± 0.4 | 0.007 | 0.020 |
| SIRT2 | 6.2 ± 1.4 | 4.9 ± 1.2 | 4.9 ± 1.1 | 0.001 | 0.018 |
| CD244 | 6.0 ± 0.4 | 5.8 ± 0.4 | 5.8 ± 0.4 | 0.002 | 0.131 |
| STAMBP | 4.6 ± 1.2 | 3.7 ± 0.9 | 3.7 ± 1.0 | 0.001 | 0.041 |
| NT3 | 1.9 ± 0.5 | 1.4 ± 0.3 | 1.6 ± 0.6 | 0.001 | 0.226 |
| MCP-1 | 8.6 ± 0.4 | 9.2 ± 0.6 | 9.1 ± 0.3 | 0.003 | 0.021 |
| MMP-10 | 8.6 ± 0.7 | 9.5 ± 0.9 | 9.2 ± 0.6 | 0.010 | 0.335 |
| CCL11 | 7.3 ± 0.4 | 8.3 ± 0.5 | 8.3 ± 0.5 | <0.001 | 0.030 |
| TGF-α | 0.8 ± 0.3 | 1.0 ± 0.2 | 0.9 ± 0.3 | <0.001 | 0.016 |
| OPG | 9.7 ±0.4 | 10.1 ± 0.5 | 10.0 ± 0.3 | 0.015 | 0.004 |
| CDCP1 | 2.0 ± 0.4 | 2.9 ± 0.7 | 3.0 ± 0.5 | 0.047 | 0.008 |
| Flt3l | 8.7 ± 0.4 | 9.2 ± 0.5 | 9.1 ± 0.5 | 0.023 | 0.055 |
| CXCL10 | 8.4 ± 0.9 | 9.3 ± 0.8 | 9.6 ± 1.0 | 0.041 | 0.015 |
| IL-18R1 | 7.2 ± 0.5 | 7.3 ± 0.6 | 7.3 ± 0.5 | 0.437 | 0.038 |
| HGF | 6.6 ± 0.4 | 7.1 ± 0.4 | 6.9 ± 0.4 | 0.017 | 0.740 |
| TNFRSF9 | 5.8 ± 0.4 | 6.3 ± 0.6 | 6.1 ± 0.5 | 0.013 | 0.338 |
| IL-10 | 3.5 ± 0.6 | 4.0 ± 0.6 | 3.8 ± 0.7 | 0.036 | 0.702 |
| IL-7 | 3.1 ± 0.8 | 3.1 ± 0.7 | 3.0 ± 0.7 | 0.047 | 0.047 |
| TNFSF14 | 2.5 ± 0.6 | 2.6 ± 0.4 | 2.3 ± 0.4 | 0.819 | 0.038 |
| EN-RAGE | 2.3 ± 1.1 | 1.9 ± 0.8 | 1.8 ± 0.5 | 0.017 | 0.013 |
HC = healthy controls, MC = microscopic colitis. Values are expressed as mean ± standard deviation. Data are expressed as Normalized Protein Expression (NPX) values. The NPX unit is an arbitrary value on a log2 scale, where a larger NPX value represents a higher protein expression. Comparisons were calculated using a general linear regression model with age as a covariate. Proteins with p-values < 0.05 in any comparison are shown. p ≤ 0.01 was considered statistically significant.