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Histamine release from human peripheral basophils in response to high IgE antibody concentrations. (a) IgE antibodies (0.05–10 μg/mL) induce histamine release from IgE antibodies-stripped basophils at concentration dependent manner. (b) IL-3 (1 ng/mL) enhanced IgE antibodies-induced histamine release. N.D. means “not detected”.
