Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 20;24(1):1. doi: 10.3390/molecules24010001

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Ultrastructural analysis of amastigotes after the treatment with compound 2. Peritoneal macrophages from BALB/c mice were infected with stationary phase L. amazonensis promastigotes and treated with compound 2 at 6 µM during 24 and 48 h. (A,B) Control amastigotes showing normal organelles, such as nuclei, mitochondria, flagellar pocket and Golgi. (C,D) Amastigotes treated with compound 2 during 24 h presenting the opening of Golgi (arrowhead) and vesicle accumulation inside the flagellar pocket, respectively. (E) Zoomed image of vesicles inside the flagellar pocket highlighting the double and multiple membrane formation. (F,G) Increased accumulation of cytoplasmic vesicles in amastigotes treated with compound 2 during 48 h. (H) Zoomed image showing a myelin-like figure in the cytoplasm of an amastigote (arrow). N, nuclei; M, mitochondria; FP, flagellar pocket; G, golgi; K, kinetoplast; V, vacuole.