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. 2019 Jan 7;20(1):187. doi: 10.3390/ijms20010187

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Impact of oxidative stress and inflammation markers on cardiovascular events or mortality. (A) Associations of derivatives of reactive oxygen metabolites (d-ROMs) levels and total thiol levels (TTL) with cardiovascular disease-specific mortality Adjustments for other confounders as described for model 1 (age and sex). d-ROMs groups [Carratelli Units]: reference, <340; T1, 341–400; T2, 401–500; T3, >500. *, p < 0.05 versus reference value. Graph was generated from tabular data in Schöttker et al. BMC Med. 2015 [38]. (B) Hazard ratios for all coronary heart disease in correlation with markers of inflammation (cytokines and chemokines: IL-6, IL-18, MMP-9, sCD40L, and TNF-α) in the Danish Research Centre for Prevention and Health cohort (1514 subjects, 833 cases). Adjustment for sex and age, log-transformed baseline levels of cytokines. Redrawn from tabular data in Kaptoge et al. Eur. Heart J. 2014 [46].