(A and B) Tabulated summary of amino-acids that yielded low average L values averaged across all ligand-free and ligand-bound simulation systems of each protein. Identified residues and respective positions were mapped within the primary sequence. Residues are underlined while positions are indicated above the residues. Continuous stretches of residue positions are indicated by colon punctuations. Residue numbering is according to E. coli DnaK sequence (UniProtKB ID: P0A6Y8). Equivalent residue numbering from complete Hsp72 and Hsc70 sequences are tabulated in Table S8A,B.