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. 2018 Dec 29;24(1):110. doi: 10.3390/molecules24010110

Figure 2.

Figure 2

Effects of SHK treatment on APAP-induced glutathione (GSH), reactive oxygen species (ROS) and myeloperoxidase (MPO) production in mice. Mice were injected with SHK (12.5 and 25 mg/Kg) for 1 h, and then injected with APAP (500 mg/Kg) for 9 h. (A) The effect of SHK on liver GSH production in APAP-treated mice. (B) SHK reduced the accumulation of APAP-induced ROS in liver. (C) SHK inhibited APAP-induced MPO production in liver. All of the data shown represent the average from five independent experiments. * p < 0.05 versus the control group; # p < 0.05 and ## p < 0.01 versus the APAP group.