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. 2018 Dec 26;20(1):83. doi: 10.3390/ijms20010083
ACTIVE Abaloparatide Comparator Trial In Vertebral Endpoints Trial
ARCH Active-Controlled Fracture Study in Postmenopausal Women with Osteoporosis at High Risk
BMD Bone mineral density
BMI Body mass index
BMP Bone morphogenetic protein
cAMP cyclic Adenosine monophosphate
ERK1/2 Extracellular-signal Regulated Kinase 1 and 2
FDA United States Food and Drug Administration
FRAME Fracture Study in Postmenopausal Women with Osteoporosis
FRAX Fracture Risk Assessment Score
GIOP Glucocorticoid-induced osteoporosis
iPTH Intermittent PTH
LRP5/6 Low-density lipoprotein receptor-related protein 5 or 6
LRP6 Low-density lipoprotein receptor-related protein 6
miRNA Micro RNA
NBD NEMO binding domain peptide
NEMO NF-kappa-B essential modulator
NF-κB Nuclear factor “kappa-light-chain-enhancer” of activated B-cells
OPG osteoprotegerin
PTH Parathyroid hormone
PTH1-34 Teriparatide, peptide Fragment of PTH
PTH1R parathyroid hormone 1 receptor
PTHrP parathyroid hormone-related protein
RANK Receptor Activator of NF-κB
RANKL Receptor Activator of NF-κB Ligand
rhBMP Recombinant BMP
Runx2 Runt-related transcription factor 2
Scl Sclerostin
STRUCTURE An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal Women
TCF/LEF T cell factor/lymphoid enhancer factor
Wnt Wingless-related integration site/Wnt signalling pathway
WT Wild type