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Values of dissociation constant (KD) and the equilibrium binding capacity (Qmax) obtained from fitting the IgG adsorption data of HWRGWV-TREN-WB, Ac-HWRGWV-TREN-WB, HWCitGWV-TREN-WB, and Ac-HWCitGWV-TREN-WB resins to a Langmuir model. Protein A-based adsorbent MabSelect SuRe, is reported for comparison.
| Ligand |
Qmax (mg·IgG/mL Adsorbent) |
KD (µM) |
|---|---|---|
| HWRGWV | 85 | 1.04 |
| Ac-HWRGWV | 72 | 1.16 |
| HWCitGWV | 49 | 0.97 |
| Ac-HWCitGWV | 50 | 1.12 |
| Protein A [59] (MabSelect SuRe) |
77 | - |
