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Serum monomeric Ln-γ2 levels were measured in 57 patients with HCC. HCC positive rates, obtained when combining two biomarkers, were compared. Three patients were negative for all three biomarkers. HCC detection rates for the combination of Ln-γ2 and PIVKA-II, Ln-γ2 and AFP, and PIVKA-II and AFP, were 89.5% (51/57), 82.5% (47/57), and 80.7% (46/57), respectively. A combination of all three markers was detected in 54/57 patients (94.7%). Figure 8 is modified from Kiyokawa et al. [22].
