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. 2019 Jan 8;20(1):226. doi: 10.3390/ijms20010226

Table 2.

Comparison of measurement efficiency between LISA and CLIA.

ELISA Automated CLIA
Dynamic range Narrow *1 Wide *2
Detection sensitivity Low High
Diagnostic accuracy Low High
Background High Low
Throughput Low High
Reaction time > 2.5 h 30 min

*1: Note that dynamic range of ELISA is 15–4000 pg/mL *2, and CLIA is 10–20,000 pg/mL.