Table 5.

Immune-related DEGs identified in this study with fold change, p-value, and their representative biological processes and molecular functions.

Entrez ID	Gene Symbol	LogFC	p-Value	Representative GO Biological Processes and Molecular Functions
51,083	GAL	−2.69	4.22 × 10−21	negative regulation of immune system process; regulation of immune process
3240	HP	−2.21	1.06 × 10−9	immune system process
2353	FOS	−1.45	2.85 × 10−7	positive regulation of immune system process; regulation of immune response
5366	PMAIP1	−1.44	4.11 × 10−7	immune effector process; immune system process
6146	RPL22	−1.42	2.91 × 10−2	immune system development; immune system process
7060	THBS4	−1.33	7.19 × 10−6	positive regulation of immune system process; regulation of immune process
10,410	IFITM3	−1.28	8.39 × 10−6	innate immune response; immune effector process; immune system process
2488	FSHB	−1.28	5.95 × 10−3	regulation of immune system process
133	ADM	−1.28	4.34 × 10−7	humoral immune response; immune response; immune system process
2719	GPC3	−1.22	3.09 × 10−9	immune system development; immune system process
7852	CXCR4	−1.22	3.24 × 10−9	immune system process
347	APOD	−1.21	2.78 × 10−5	negative regulation of immune system process; regulation of immune process
9353	SLIT2	−1.21	6.81 × 10−10	negative regulation of immune system process; regulation of immune process
8324	FZD7	−1.21	1.74 × 10−8	immune system development; immune system process
2197	FAU	−1.19	1.35 × 10−2	humoral immune response; innate immune response in mucosa
4783	NFIL3	−1.14	8.44 × 10−5	immune response; immune system process
6218	RPS17	−1.13	2.70 × 10−2	immune system process
5950	RBP4	−1.08	1.79 × 10−2	positive regulation of production of molecular mediator of immune response
5919	RARRES2	−1.06	4.34 × 10−7	positive regulation of immune system process; regulation of immune process
3669	ISG20	−1.03	8.23 × 10−8	innate immune response; immune effector process; immune system process
3059	HCLS1	−1.02	6.70 × 10−5	positive regulation of immune system process; regulation of immune process
6279	S100A8	−1.01	1.99 × 10−3	innate immune response; immune response; immune system process
710	SERPING1	−1.00	6.70 × 10−6	adaptive immune response; b cell mediated immunity; humoral immune response
716	C1S	−1.00	5.90 × 10−4	adaptive/innate immune response; Leukocyte mediated immunity
7056	THBD	−1.00	2.52 × 10−6	immune system process
715	C1R	−0.98	3.31 × 10−6	adaptive/innate immune response; positive regulation of immune system process
1672	DEFB1	−0.92	1.44 × 10−4	humoral immune response; innate immune response in mucosa
2669	GEM	−0.89	2.22 × 10−4	immune response; immune system process
1958	EGR1	−0.86	2.45 × 10−3	innate immune response; immune response; immune system development
6662	SOX9	−0.86	3.43 × 10−4	negative regulation of immune system process; regulation of immune process
3426	CFI	−0.84	6.05 × 10−10	adaptive immune response; leukocyte/lymphocyte mediated immunity
7412	VCAM1	−0.84	6.87 × 10−7	innate immune response; positive regulation of immune system process
1366	CLDN7	−0.84	4.27 × 10−3	regulation of immune effector process; regulation of immune system process
3726	JUNB	−0.84	2.43 × 10−5	immune system development; immune system process
9796	PHYHIP	−0.82	2.78 × 10−3	regulation of immune effector process; regulation of immune system process
7049	TGFBR3	−0.81	3.58 × 10−3	immune response; immune system development; immune system process
3958	LGALS3	−0.80	4.63 × 10−2	innate immune response; negative regulation of immune effector process
3485	IGFBP2	−0.78	1.23 × 10−3	positive regulation of immune system process; regulation of immune process
1051	CEBPB	−0.75	2.38 × 10−3	negative regulation of immune system process; regulation of immune process
302	ANXA2	−0.72	1.55 × 10−2	immune system development; immune system process
5806	PTX3	−0.72	2.46 × 10−3	innate immune response; immune effector process; immune system process
3320	HSP90AA1	−0.71	1.90 × 10−2	positive regulation of immune system process; activation of immune response
7704	ZBTB16	−0.69	3.81 × 10−2	negative/positive regulation of immune system process
8543	LMO4	−0.69	1.35 × 10−2	immune system development; immune system process
6223	RPS19	−0.69	1.25 × 10−2	regulation of innate immune response; immune system development
4057	LTF	−0.68	3.41 × 10−2	humoral immune response; innate immune response in mucosa
100,133,941	CD24	−0.65	5.68 × 10−3	positive regulation of immune system process; immune system process
684	BST2	−0.64	8.65 × 10−3	humoral/innate immune response; negative regulation of immune response
23,543	RBFOX2	0.59	5.42 × 10−3	regulation of immune system process
5747	PTK2	0.59	1.12 × 10−2	activation of immune response; positive regulation of immune response
2047	EPHB1	0.60	8.01 × 10−3	immune system process; immunological synapse formation
27,242	TNFRSF21	0.60	4.66 × 10−3	adaptive/humoral immune response; negative regulation of immune process
8754	ADAM9	0.61	1.68 × 10−2	immune system process
3175	ONECUT1	0.64	1.36 × 10−3	immune system development; immune system process
54,861	SNRK	0.64	1.61 × 10−2	immune system development; immune system process
801	CALM1	0.64	6.76 × 10−4	immune response regulating cell surface receptor signaling pathway
51,752	ERAP1	0.65	2.84 × 10−2	regulation of innate immune response; regulation of immune system process
7456	WIPF1	0.65	1.59 × 10−3	activation of immune response; immune system process
4982	TNFRSF11B	0.66	3.67 × 10−2	immune response; immune system process
6362	CCL18	0.67	3.72 × 10−2	innate immune response; immune response; immune system process
30,849	PIK3R4	0.67	2.02 × 10−2	activation/positive regulation of innate immune response
5594	MAPK1	0.71	2.18 × 10−3	regulation of immune system process; immune system development
8563	THOC5	0.71	7.07 × 10−3	immune system development; immune system process
8473	OGT	0.72	1.16 × 10−2	positive regulation of immune system process
5795	PTPRJ	0.78	1.01 × 10−2	negative/positive regulation of immune system process
4684	NCAM1	0.81	5.74 × 10−3	innate immune response; immune response; immune system process