Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 21;20(1):40. doi: 10.3390/ijms20010040

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Stages of the translation elongation cycle; (A,B) binding of the aa-tRNA·EF-Tu·GTP ternary complex to the A/T site; (C) conformational closing of the 30S subunit and forming the codon-anticodon A-site latch; (D) elbow accommodation of aa-tRNA; (E) full CCA accommodation of aa-tRNA to the A/A-site, release of EF-Tu·GDP, entry of EF-G·GTP; (F) peptidyl transfer; (G) EF-G·GTP→GDP and onset of translocation, opening of the codon-anticodon latch, formation of hybrid tRNA states pe/E and ap/A or ap/ap; (H) full forward and reverse translocation. Some intermediate x-ray or cryo-electron microscopy structures are shown.