Skip to main content
. 2018 Dec 20;24(1):7. doi: 10.3390/molecules24010007

Table 3.

Pharmacokinetic parameters of oral administration (Mean ± SD, n = 4).

Formulation Tmax (0–72 h) (h) Cmax (0–72 h) (ng/mL) AUC0→t (µg·h/mL) t1/2 (h)
Oral 4.9 ± 0.8 48.6 ± 12.1 d 0.6 ± 0.2 d 11.0 ± 1.9 d
NS-PA-L 14.5 ± 0.0 1104.7 ± 162.5 a 192.3 ± 21.8 a 170.5 ± 16.7 a
NS-PB-L 14.5 ± 0.0 518.9 ± 109.7 a,†,b 153.2 ± 20.2 a,b 222.0 ± 23.3 a,b
NS-PC-L 14.5 ± 0.0 685.5 ± 60.9 †,c 163.0 ± 29.7 c 406.8 ± 34.2 b
NS-PB-S 7.0 ± 2.0 189.4 ± 32.5 b 98.5 ± 21.2 b 208.8 ± 17.4
NS-PC-S 9.0 ± 2.0 232.9 ± 122.2 c 110.2 ± 32.1 c 266.9 ± 44.4
NS-Hα-1 6.0 ± 0.0 218.5 ± 31.9 113.1 ± 14.5 241.5 ± 39.2
NS-Hα-2 7.0 ± 2.0 209.7 ± 24.2 d 96.9 ± 9.8 d 252.3 ± 48.8 d

p < 0.1, a,b,c,d p < 0.05.