HIF-1α | Hypoxia inducible factor-1 alpha |
NSCLC | Non-small cell lung cancer |
VEGF | Vascular endothelial growth factor |
PHD | Prolyl hydroxylase |
pVHL | von Hippel–Lindau protein |
ARNT | Aryl hydrocarbon receptor nuclear translocator |
HREs | Hypoxia response elements |
RT-PCR | Reverse transcription-polymerase chain reaction |
GLUT-1 | Glucose transporter 1 |
PDGF | Platelet-derived growth factor |
UPS | Ubiquitin-proteasome system |
SUMO | Small ubiquitin-like modifier |
SENP-1 | Sentrin/SUMO-specific protease 1 |