Table 1.
Variable | Patients with Active Disease | Patients in Remission | |
---|---|---|---|
Biopsies Taken from both Active and Inactive Regions | Biopsies Taken from Active Regions only | Biopsies Taken from Inactive Regions | |
Patients, n | 30 | 4 | 10 |
Age (years) | 50 ± 18 | 39 ± 21 | 49 ± 11 |
Gender | |||
female | 16 | 2 | 6 |
male | 14 | 2 | 4 |
Smoker, n (%) | 1 (3) | 0 | 1 (10) |
Disease extent * | |||
Proctitis only | 7 (23) | - | - |
Proctosigmoiditis | 14 (47) | - | - |
Left-sided colitis | 8 (27) | - | - |
Pancolitis | 1 (3) | 4 (100) | 4 (100) |
Current Medication for UC | |||
Untreated | 12 (40) | 2 (50) | 3 (30) |
Aminosalicylates (5-ASA) | 16 (53) | 1 (25) | 5 (50) |
Corticosteroids | 6 (20) | 2 (50) | 3 (30) |
Immunomodulator therapy | 4 (13) | - | - |
Topical therapy | 0 | - | - |
Biologic therapy | 0 | - | - |
Antibiotics/probiotics/vitamin supplements | 6 | - | 1 |
Age and disease duration data are shown as mean value ± SD. Other data indicates the number of patients. Group percentages are shown in brackets. * Disease Extent: Proctitis: Disease only in the rectum; Proctosigmoiditis: Disease in the rectum and sigmoid colon; Left-sided colitis: Limited or distal colitis. Disease in left side of the colon; Pancolitis: Disease in the entire colon.