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. 2019 Jan 2;20(1):139. doi: 10.3390/ijms20010139

Table 3.

Some representative in-cell NMR studies.

System Experimental Outcome Reference
E. coli Heteronuclear spectra of proteins were collected in living cells [66]
E. coli Protein structure was determined in living cells [68]
Mammalian cells In-cell NMR study of proteins that were delivered into cells was performed [93]
Oocyte Lanthanide tag was used in generating distance restraints in living cells [115]
HEK293T Protein was overexpressed in mammalian cells for in-cell NMR studies [116]
E. coli In-cell NMR was used to screening a library [84]
M. smegmatis The first application of in-cell NMR in target engagement [117]
Hela In-cell NMR study on DNA was carried out [101]