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Experimental plan of low LET proton radiation exposure of in vitro lung vascular networks (flow-adapted endothelial cells) and LGM2605 treatment. FAECs were exposed to 0 Gy or 1 Gy low LET (3–4 keV/µm) proton radiation and treated with 0 µM or 100 µM LGM2605 30 min following radiation exposure. Cells were harvested 24 h post radiation exposure and evaluated for inflammation and inflammasome activation.
