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. 2019 Jan 17;2(1):e201800131. doi: 10.26508/lsa.201800131

Figure 1. Identification of proteins associated with transcripts encompassing the subdomains of domain 3.

Figure 1.

(A) Schematic representation of the modular domains of the FMDV IRES element. Subdomains of domain 3 are highlighted by color lines surrounding the corresponding secondary structure. The following color code is used: purple for SL3a, blue for SL3abc, green for SL123, and orange for D3. Numbers indicate the nucleotide position included on each transcript. (B) Overview of the RNA-binding protein purification protocol. A representative image of silver-stained gel loaded with proteins associated with control RNA, SL3abc, and SL3a transcripts after streptavidin-aptamer purification is shown. (C) Venn diagram showing the number of factors associated with each subdomain.