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. 2019 Jan 18;18:12. doi: 10.1186/s12943-018-0937-3

Table 1.

Overview of adhesion molecules found on different leukocyte subtypes and their corresponding ligands

Leukocyte Adhesion Molecule Leukocyte Subtype Ligand
VLA-4 (α4ß1) Monocytes [39]
Neutrophils in case of sepsis [38]
VCAM-1
MAdCAM-1
JAM-B
LFA-1 (αLß2) (CD11a/CD18) Neutrophils [39, 42]
Monocytes [43]
ICAM-1
ICAM-2
JAM-A
α4ß7 (CD49d/ß7) Lymphocytes (CD4 and CD8 T cells) (mucosal lymphoid nodules) [7, 44] MAdCAM-1
Gp150,95 (αXß2)
(CD11c/CD18)
Monocytes
Macrophages [45]
Granulocytes [46] (Neutrophils [9])
Langerhans cells
iC3b
(JAM-C [47])
αMß2 (mac-1)
(CD11b/CD18)
Monocytes [43]
Macrophages [45]
Granulocytes [48]
(Neutrophils [42])
Langerhans cells [7]
iC3b
ICAM-1
ICAM-2
JAM-C
αDß2 Macrophages (?) [7]
Neutrophils [9]
ICAM-3
CD47 T cell [49] VCAM-1
ICAM-1
L1-CAM Lymphocytes [4, 50, 51] α5ß1 (VLA-5)
αVß3
Glycosylated proteins
(ß-galactose)
Leukocytes [52] Galectins

Only major ligands are listed