Fig. 5.

Predicated function and multiple biological pathways in three groups. a Venn diagram of the predicated multiple biological pathways. b Annotated of multiple biological pathway distribution in seven major categories. c Heatmap of the top 35 biological pathways across three groups. d The relationship between top 35 biological pathways and genera at the criteria of P < 0.050 by Wilcoxon rank sum test in top 35. ⁺P < 0.050; ⁺⁺P < 0.010; ⁺⁺⁺P < 0.001 by Spearman’s correlation analysis. e Heatmap of multiple biological pathways across three groups at the P < 0.100 by Wilcoxon rank sum test. Multiple biological pathways at P < 0.050 by Wilcoxon rank sum test are marked with light green star, P < 0.001 with dark star. Red in color relates with amino acid metabolism, green in color relates to glucose metabolism