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. 2019 Jan 17;19:27. doi: 10.1186/s12862-019-1353-z

Table 2.

Reciprocal best hits (BRBH) to human PLG activator group members in lower chordates

Animal group Species BRBH Protein domain types
Cephalochordates Branchiostoma belcheri tPA SRCR, Kringle, LDLRA, PAN, Trypsina
HABP2 SRCR, Kringle, LDLRA, PAN, Trypsin
Branchiostoma floridae HGFAC SRCR, Kringle, LDLRA, Trypsina
Assymetron lucayanum HABP2 SRCR, Kringle, LDLRA, PAN, Trypsin
Urochordates Ciona intestinalis HABP2 FN2, PAN, Kringle, Trypsin
Oikopleura dioica HABP2 Kringle, Trypsin

aindicates Trypsin domain predicted to be non-functional. SRCR (scavenger receptor cysteine-rich domain), LDLRA (Low-density lipoprotein (LDL) receptor class A), FN2 (fibronectin type 2 domain)