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. 2019 Jan 18;5:9. doi: 10.1186/s40814-018-0382-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Overview of the study design. After screening, participants are randomized to either the hydrocortisone conditioning group or the placebo control group. Each group undergoes six experimental sessions. During the acquisition phase (week 1), the hydrocortisone conditioning group is administered a capsule containing 100 mg of hydrocortisone (unconditioned stimulus, UCS) combined with a distinctively tasting beverage (conditioned stimulus, CS), whereas the placebo control group receives an identically looking placebo capsule and the same beverage. During the evocation phase (week 2), all participants receive a placebo capsule and the beverage. In the final session, all participants are exposed to a psychosocial stress task

Inline graphic — Overview of the study design. After screening, participants are randomized to either the hydrocortisone conditioning group or the placebo control group. Each group undergoes six experimental sessions. During the acquisition phase (week 1), the hydrocortisone conditioning group is administered a capsule containing 100 mg of hydrocortisone (unconditioned stimulus, UCS) combined with a distinctively tasting beverage (conditioned stimulus, CS), whereas the placebo control group receives an identically looking placebo capsule and the same beverage. During the evocation phase (week 2), all participants receive a placebo capsule and the beverage. In the final session, all participants are exposed to a psychosocial stress task