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letter
. 2018 Oct 5;74(2):521–523. doi: 10.1093/jac/dky420

Figure 1.

Figure 1

(a) Predicted ORFs surrounding the npmA gene (dark grey) in CD7814 (light grey), the E. coli pARS3 plasmid (black) and five C. difficile genomes of human and animal origin (white). Shaded areas highlight regions of sequence homology. Chequered arrows indicate ORFs encoding recombinases potentially associated with horizontal transfer of npmA into CD7814. hu, human; sw, swine; bv, bovine; US, USA, JP, Japan; AU, Australia; CA, Canada. (b) NpmA protein alignment depicting the K131N substitution in CD7814 and E. coli pARS3.