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PTA for 5000 simulated cSSTI patients with normal renal function achieving PK/PD targets for S. aureus by MIC following administration of ceftaroline fosamil 600 mg q12h 1 h iv infusion, overlaid with ceftaroline MIC distributions for S. aureus collected from the 2013 AWARE surveillance study in Europe and the Asia Pacific region. The ceftaroline MIC90 values for all S. aureus isolates and the MRSA subset were 1 mg/L and 2 mg/L in Europe and the Asia Pacific region, respectively.
