Table 2.

PTA for 5000 simulated cSSTI patients with normal renal function achieving PK/PD targets for S. aureus by MIC following administration of ceftaroline fosamil 600 mg q12h 1 h iv infusion

Ceftaroline MIC (mg/L)	PTA (%)
	stasis (27% fT>MIC)	1 log10 kill (31% fT>MIC)	2 log10 kill (35% fT>MIC)
0.015	100	100	100
0.03	100	100	100
0.06	100	100	100
0.125	100	100	100
0.25	100	100	100
0.5	100	100	100
1	100	100	100
2	98.9	96.1	92.5
4	66.5	49.5	37.1
8	4.84	2.14	1.04
16	0.04	0	0