Table 3.

PTA for 5000 simulated cSSTI patients with normal renal function achieving PK/PD targets for S. aureus by MIC following administration of ceftaroline fosamil 600 mg q8h 2 h iv infusion

Ceftaroline MIC (mg/L)	PTA (%)
	stasis (27% fT>MIC)	1 log10 kill (31% fT>MIC)	2 log10 kill (35% fT>MIC)
0.015	100	100	100
0.03	100	100	100
0.06	100	100	100
0.125	100	100	100
0.25	100	100	100
0.5	100	100	100
1	100	100	100
2	100	100	100
4	98.7	96.8	93.6
8	42.9	33.1	23.4
16	0.72	0.38	0.22