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Atorvastatin improved hypertension in SHR rats. Systolic blood pressure was monitored for 6 weeks. *** P<0.001 SHR vs. WKY. ## P<0.01, ### P<0.001 Ato (10, 25, 50 mg/kg/d) vs. SHR. &&& P<0.001 Ato (50 mg/kg/d) + AG490 vs. Ato (50 mg/kg/d). WKY – control group; SHR – SHR model group; Ato – atorvastatin with 10, 25, 50 mg/kg per day. Ato+Ag490 – AG490 as a STAT3 inhibitor co-treated with Atorvastatin in SHR.
