Skip to main content
. 2019 Jan 11;25:324–332. doi: 10.12659/MSM.912624

Table 1.

Assessment of fangchinoline effect on microarchitectural parameters and BMD on the prednisolone-induced osteoporosis rat model.

Sr. No. Group Bone surface density (mm−1) Trabecular bone tissue volume density (%) Trabecular number (mm−1) Trabecular thickness (mm) BMD (g/cm3)
1 Control group 3.92±0.42 37.21±2.97 1.42±0.036 0.279±0.041 0.297±0.013
2 Prednisolone group 2.36±0.28## 22.49±1.42## 0.83±0.028## 0.246±0.017# 0.128±0.007##
3 Fangchinoline 1 mg/kg 2.61±0.33 26.33±1.69 0.94±0.019 0.258±0.023 0.163±0.004*
4 Fangchinoline 3 mg/kg 3.17±0.29** 32.84±2.16** 1.27±0.023** 0.264±0.014* 0.236±0.011**
5 Fangchinoline 10 mg/kg 3.72±0.32** 36.42±2.46** 1.58±0.031** 0.283±0.031* 0.273±0.017**

Mean ±SEM (n=10).

##

p<0.01 vs. control group;

*

p<0.05

**

p<0.01 vs. prednisolone group.