Table 2.
Relationships between reproductive factors and expression of PR and NF2.
| PR | NF2 | ||||||
|---|---|---|---|---|---|---|---|
| Reproductive factors | N | Mean (95% CI) | P1 | P2 | Mean (95% CI) | P1 | P2 |
| AGE OF MENARCHE (YEARS) | |||||||
| <12 | 4 | 6.39 (3.87–8.90) | 0.71* | 0.29* | 8.98 (4.11–13.9) | 0.11* | 0.08* |
| 12–15 | 62 | 6.68 (5.55–7.82) | 11.3 (9.06–13.5) | ||||
| >15 | 48 | 6.98 (5.56–8.40) | 13.5 (10.8–16.3) | ||||
| LENGTH OF MENSTRUAL CYCLE (DAYS) | |||||||
| <28 | 8 | 7.01 (5.13–8.88) | 0.79* | 0.89* | 11.1 (7.47–14.8) | 0.54* | 0.89* |
| 28 | 77 | 6.84 (5.84–7.84) | 11.9 (9.95–13.9) | ||||
| >28 | 16 | 6.67 (5.34–8.00) | 12.7 (10.1–15.3) | ||||
| Irregular | 11 | 6.50 (4.09–8.91) | 13.4 (8.73–18.1) | ||||
| USE OF HORMONAL CONTRACEPTION | |||||||
| No | 18 | 6.21 (3.78–8.64) | 0.43 | 0.43 | 14.7 (10.4–19.2) | 0.16 | 0.12 |
| Yes | 79 | 7.28 (6.12–8.45) | 11.2 (9.13–13.4) | ||||
| HORMONAL CONTRACEPTION | |||||||
| Progesterone injection | 70 | 6.46 (4.43–8.48) | 0.27 | 0.27 | 13.9 (10.2–17.5) | 0.22 | 0.21 |
| Implant/Pills/others | 9 | 7.32 (6.08–8.55) | 11.2 (8.94–13.4) | ||||
| DURATION OF PROGESTERONE INJECTIONS (YEARS) | |||||||
| 0–10 | 80 | 7.26 (6.20–8.35) | 0.049* | 0.05* | 13.1 (10.9–15.2) | 0.046 | 0.05 |
| 10–20 | 23 | 6.10 (4.85–7.36) | 10.7 (8.25–13.1) | ||||
| >20 | 11 | 4.94 (2.51–7.36) | 8.31 (3.57–13.0) | ||||
| Per 5 years increase | −0.53 (−1.13–0.08) | 0.08 | 0.08 | −1.03 (−2.20–0.15) | 0.08 | 0.09 | |
*
P-value for trend.
P1 unajusted.
P2 adjusted for age of menarche, number of children, length of menstrual cycle, duration of exogenous progesterone, family history of breast cancer.
The bold values are the values that statistically significant.