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. 2019 Jan 10;10:427. doi: 10.3389/fnagi.2018.00427

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Copyright © 2019 Jia, Li, Li, Liang and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased functional connectivity (FC) in the seed region of the Lt.PCu in the Rt.Caud/Put specific to PD-MCI compared to HC and PD-NC. Box plots with whiskers min to max show the FC values between the Lt.PCu and the Rt.Caud/Put in the three groups and scatterplots show the relationship between the FC strength in the two regions and WMS logical memory performances in patients with PD-MCI after controlling for education and depression score. Lt, left; Rt, right; PCu, precuneus; Caud, caudate; Put, putamen; HC, healthy control; PD-NC, Parkinson’s disease with normal cognition; PD-MCI, Parkinson’s disease with mild cognitive impairment. **p < 0.01; ***p < 0.001.