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. Author manuscript; available in PMC: 2019 Jan 18.
Published in final edited form as: J Hypertens. 2017 Jul;35(7):1390–1401. doi: 10.1097/HJH.0000000000001324

FIGURE 1.

FIGURE 1

Endothelin-1 overexpression increased SBP. SBP was assessed by telemetry for 24 h a week before tamoxifen treatment and at weekly intervals thereafter for 5 weeks in control, eET-1, smPparγ−/− and eET-1/smPparγ−/− mice.Week 0 refers to blood pressure acquired the week prior to tamoxifen treatment, and week 1 refers to blood pressure acquired immediately after the last day of 5 days of tamoxifen treatment. Each point represents the average SBP over a consecutive 24-h period. Data are presented as means ± SEM, n = 4-5. *P< 0.05 vs Ctrl. Statistical differences were determined by comparing the blood pressure curves between groups.