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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Circ Cardiovasc Imaging. 2019 Jan;12(1):e007835. doi: 10.1161/CIRCIMAGING.118.007835

Figure 4. Quantitative histological analysis of PET-positive/CT-negative areas of carotid endarterectomy sample.

Figure 4.

A, Location of section taken for histological analysis of carotid endarterectomy sample. B, Confocal microscopy imaging of carotid endarterectomy section after incubation with a NIRF calcium tracer (scale bar 2 mm). C, Autoradiography imaging of the same histological section after incubation with 18F-fluoride (scale bar 2 mm). D, Confocal and autoradiography images were divided into four quadrants and each quadrant of the images was quantified (scale bars 2 mm). E, Linear correlation between NIRF signal and 18F-fluoride autoradiography signal (Pearson R = 0.8048, p = 0.0124; n = 6 histological sections were analyzed).