Table 8.
Association of FVII polymorphism with warfarin response during the maintenance phase of therapy of 129 cardiovascular patients
| Gene | Genotype | Poor responder | Good responder | Extensive responder | P-valuea |
|---|---|---|---|---|---|
|
| |||||
| FVII | H5H5 | 2/6 (33.3%) | 4/6 (66.7%) | 0/6 (0.0%) | 0.296 |
| H6H6 | 3/59 (5.2%) | 52/59 (87.9%) | 4/59 (6.9%) | ||
| H7H7 | 1/14 (7.1%) | 13/14 (92.9%) | 0/14 (0.0%) | ||
| H8H8 | 0/2 (0.0%) | 2/2 (100.0%) | 0/2 (0.0%) | ||
| H6H7 | 2/45 (4.4%) | 41/45 (91.2%) | 2/45 (4.4%) | ||
| H5H6 | 1/3 (33.3%) | 2/3 (66.7%) | 0/3 (0.0%) | ||
Note:
a
Fisher’s exact test with P<0.05 is considered significant.