Figure 1.

(A) Activities of mitochondrial enzymes in blood platelets of patients with BD in depressive episode, patients with MDD, and controls. (B) Activities of mitochondrial complexes normalized for CS activity in blood platelets of patients with BD in depressive episode, patients with MDD, and controls.

Notes: Complex I – NADH:ubiquinone reductase, complex II – succinate dehydrogenase (quinone), and complex IV – cytochrome c oxidase. Mean ± SD is shown (24 BD patients, 68 MDD patients, and 104 controls). Significantly different mean values are marked by *P<0.05, **P<0.01, and ***P<0.001.

Abbreviations: BD, bipolar disorder; C, complex; CS, citrate synthase; MDD, major depressive disorder.