Table 2.
Univariate analysis of the training cohort
| Variables | β | SE | P-value |
|---|---|---|---|
|
| |||
| Statistically nonsignificant factors | |||
| Age (years) | −0.00214 | 0.00682 | 0.7537 |
| Sex | −0.01127 | 0.20379 | 0.9559 |
| Height (cm) | 0.02084 | 0.01149 | 0.0699 |
| Weight (kg) | 0.00349 | 0.00757 | 0.6449 |
| BMI (kg/m2) | −0.00873 | 0.02468 | 0.7235 |
| PLT (×109/L) | −0.00220 | 0.00123 | 0.0735 |
| AST (U/L) | 0.00034 | 0.00040 | 0.3950 |
| HBsAg | 0.22708 | 0.20379 | 0.2651 |
| Tumor number | 0.35162 | 0.20395 | 0.0847 |
| Tumor capsule | 0.36457 | 0.18973 | 0.0547 |
| Cirrhosis | −0.11200 | 0.17002 | 0.5101 |
| History of alcohol abuse | −0.00628 | 0.15346 | 0.9673 |
| Antiviral therapy | 0.16645 | 0.15298 | 0.2766 |
| Anti-HCV (IgG) | 0.00542 | 0.45442 | 0.9905 |
| Statistically significant factors | |||
| Tumor size (cm) | 0.12838 | 0.01863 | <0.0001 |
| AFP (ng/mL) | 0.47461 | 0.16918 | 0.0050 |
| PT (seconds) | 0.21997 | 0.05446 | <0.0001 |
| Fibrinogen (g/L) | 0.19352 | 0.05718 | 0.0007 |
| ALB (g/L) | −0.09261 | 0.01288 | <0.0001 |
| TBil (μmol/L) | 0.03364 | 0.00705 | <0.0001 |
| TC (mmol/l) | −0.16744 | 0.08316 | 0.0441 |
| ALT (U/L) | 0.00272 | 0.00101 | 0.0071 |
| γ-GT (U/L) | 0.00057 | 0.00027 | 0.0331 |
| S-index | −1.30610 | 0.17261 | <0.0001 |
| Ascites | 0.60656 | 0.19005 | 0.0014 |
| PVTT | 1.47896 | 0.33065 | <0.0001 |
| Invasion of adjacent | 1.01903 | 1.01903 | 0.0007 |
| tissues | |||
| MVI | 0.85045 | 0.19929 | <0.0001 |
| Intrahepatic transfer | 0.72404 | 0.16483 | <0.0001 |
| Tumor grade | 0.61275 | 0.15390 | <0.0001 |
Abbreviations: γ-GT, γ-glutamyl transpeptidase; AFP, alpha-fetoprotein; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; HCV, hepatitis C virus; MVI, microvascular invasion; PLT, platelet; PT, prothrombin time; PVTT, portal vein tumor thrombus; SE, standard error; TBil, total bilirubin; TC, total cholesterol.