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3-HK levels in the maternal plasma (A), placenta (B), fetal plasma (C) and fetal brain (D) 90 minutes after oral treatment of pregnant CD-1 mice on ED18 with either saline (vehicle), kynurenine (100 mg/kg) or KYNA (10 mg/kg). Data are the mean ± SEM (n=3 dams per group; n=3 embryos per dam). *p<0.05, **p<0.01 (one-way Anova, followed by Bonferroni’s post-hoc test).
